Title:
皮膚疾患を治療するためのヘポキシリンとICHTHYINのモデュレータ
Document Type and Number:
Japanese Patent JP4903136
Kind Code:
B2
Abstract:
The present application relates to compositions and methods for treating skin disorders, ,dry skin, and protection of skin in inflammatory events. The present application more particularly discloses the identification of new genes and metabolic pathways involved in skin disorders, which provide novel targets and approaches for treating said disorders and for screening biologically active compounds. The present invention also provides various products and constructs, such as probes, primers, vectors, recombinant cells, which can be used to implement the above methods. The invention may be used to detect or treat various skin disorders, particularly dry and inflammatory skin disorders, in various subjects, including mammalian subjects, particularly human beings.
Inventors:
Fisher, Eudis
Application Number:
JP2007514211A
Publication Date:
March 28, 2012
Filing Date:
June 03, 2005
Export Citation:
Assignee:
INSERM(INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)
International Classes:
C12Q1/68; A61K31/557; C07K16/28; C12N15/00; C12N15/09; G01N33/50; G01N33/68
Other References:
菅原照夫 外1名,X染色体性魚鱗癬症の遺伝子診断,医学のあゆみ,日本,1992年12月,Vol.163,No.11,P.840
山西清文,『トランスグルタミナーゼ1異常症における魚鱗癬の発症病態』,生化学,日本,2001年 8月25日,Vol.73,No.8,P.670,S61-5
山本明美,総説『角化異常症と辺縁帯の異常』,電子顕微鏡,日本,2000年11月30日,Vol.35,No.3,P.215-220
山西清文,『トランスグルタミナーゼ1異常症における魚鱗癬の発症病態』,生化学,日本,2001年 8月25日,Vol.73,No.8,P.670,S61-5
山本明美,総説『角化異常症と辺縁帯の異常』,電子顕微鏡,日本,2000年11月30日,Vol.35,No.3,P.215-220
Attorney, Agent or Firm:
Hajime Tsukuni
Koshiro Tsukuda
Fusayuki Saito
Fusayuki Saito
Koshiro Tsukuda
Fusayuki Saito
Fusayuki Saito