Title:
微造粒ポリマーの形成方法
Document Type and Number:
Japanese Patent JP4903424
Kind Code:
B2
Abstract:
A method for formation of micro-prilled poloxamer particles is disclosed. The particles find special use in pharmaceutical formulations. The process involves use of atomizing nozzles at higher than normal pressure atomizing gas, high atomizing gas temperature, use of high feed temperatures to reduce the viscosity of the poloxamer and optionally sieving after prill formation in prilling towers. The poloxamer particles are spherical and preferably have an average nominal diameter of less than or equal to 106 microns. The process is very cost effective and rapid.
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Inventors:
Rudolph Ernest Lisa
Anisul Quadil
Rebecca ham shepherd
Peter Gudesiowski
Anisul Quadil
Rebecca ham shepherd
Peter Gudesiowski
Application Number:
JP2005342508A
Publication Date:
March 28, 2012
Filing Date:
November 28, 2005
Export Citation:
Assignee:
BASF SE
International Classes:
A61K47/34; A61K9/14; A61K9/20
Domestic Patent References:
JP2004523594A | ||||
JP8501073A | ||||
JP2000504038A | ||||
JP2000507991A |
Foreign References:
WO2004028505A1 | ||||
WO2003028645A1 | ||||
US20030054045 | ||||
US20010006617 | ||||
WO1995009044A1 |
Other References:
Internationale jahrestagung - Institut fuer chemie der treib- und explosivstoffe,1978,pages 277-299,Database CAPLUS on STN, AN 1979:525526
Attorney, Agent or Firm:
Yusuke Hiraki
Ishii Teiji
Satoshi Fujita
Ishii Teiji
Satoshi Fujita