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Title:
ステアロイル-CoAデサチュラーゼ酵素によって媒介される疾患の処置のための複素環誘導体
Document Type and Number:
Japanese Patent JP4958784
Kind Code:
B2
Abstract:
Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (I): where x, y, G, J, K, L, M, W, V, R 2 , R 3 , R 5 , R 5a , R 6 , R 6a , R 7 , R 7a , R 8 and R 8a are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.

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Inventors:
Cambogi, legend
Chang, Zai Hoi
Huh, Chian-Min
Kodomur, Vishnu Mercy
Liu, Seefen
Sun, Xiaoy
Chukka, Nagasley
Application Number:
JP2007532631A
Publication Date:
June 20, 2012
Filing Date:
September 20, 2005
Export Citation:
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Assignee:
XENON PHARMACEUTICALS INC.
International Classes:
C07D231/38; A61K31/496; A61P1/16; A61P3/04; A61P3/06; A61P3/10; A61P43/00; C07D271/10; C07D285/12; C07D285/135
Domestic Patent References:
JP2002506858A
JP2004123732A
JP2003532723A
JP2004527511A
JP2000119253A
Foreign References:
WO2004018453A1
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita



 
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