Title:
乳酸の製造法
Document Type and Number:
Japanese Patent JP5014998
Kind Code:
B2
Abstract:
The present invention provides microorganisms, in which the activity of 4-hydroxybenzoate polyprenyltransferase or 2-octaprenylphenol2-octaprenyl-6-methoxyphenol flavin reductase is reduced or lost, and which have an ability to produce lactic acid, in particular, microorganisms comprising a chromosomal DNA in which a gene encoding a protein having 4-hydroxybenzoate polyprenyltransferase activity or a protein having 2-octaprenylphenol2-octaprenyl-6-methoxyphenol flavin reductase activity is partially or completely defective; and a process for producing lactic acid using the microorganisms.
Inventors:
Ito Mikito
Kimie Masuda
Hideo Mori
Kato Makiko
Kimie Masuda
Hideo Mori
Kato Makiko
Application Number:
JP2007534411A
Publication Date:
August 29, 2012
Filing Date:
September 05, 2006
Export Citation:
Assignee:
Kyowa Hakko Kirin Co., Ltd.
International Classes:
C12N15/09; C12N1/21; C12P7/56
Other References:
Journal of General Microbiology,1993年,Vol.139,p.1795-1805
Journal of Bacteriology,1998年,Vol.180, No.14,p.3681-3685
FEMS Microbiology Letters,2001年,Vol.203,p.131-139
Journal of Bacteriology,2000年,Vol.182, No.18,p.5139-5146
Applied and Enviromental Microbiology,1999年,Vol.65, No.4,p.1384-1389
Journal of Bacteriology,1998年,Vol.180, No.14,p.3681-3685
FEMS Microbiology Letters,2001年,Vol.203,p.131-139
Journal of Bacteriology,2000年,Vol.182, No.18,p.5139-5146
Applied and Enviromental Microbiology,1999年,Vol.65, No.4,p.1384-1389
Attorney, Agent or Firm:
Hatsushi Shimizu
Toshi Gobe
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Ryuichi Inoue
Toshi Gobe
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Ryuichi Inoue