Title:
抗IL-23抗体
Document Type and Number:
Japanese Patent JP5022367
Kind Code:
B2
Abstract:
The present invention encompasses isolated antibodies, or antigen-binding portions thereof, that specifically bind to the p19 subunit of IL-23. These antibodies, or antigen-binding portions thereof, are high affinity, neutralizing antibodies useful for the treatment of autoimmune disease.
Inventors:
Catherine Brutigham Badler
Stuart Willis Bright
Craig Duane Dickinson
Christine Kay Kickley
David Matthew Marquis
Alan Philippe Waslow
Stuart Willis Bright
Craig Duane Dickinson
Christine Kay Kickley
David Matthew Marquis
Alan Philippe Waslow
Application Number:
JP2008528064A
Publication Date:
September 12, 2012
Filing Date:
August 23, 2006
Export Citation:
Assignee:
Eli Lilly and Company
International Classes:
C07K16/24; A61K39/395; A61P37/00; C07K16/46; C12N15/09; C12P21/08
Domestic Patent References:
| JP2009523012A | ||||
| JP2010518865A | ||||
| JP2007523088A |
Foreign References:
| WO2004081190A1 | ||||
| WO2004071517A1 | ||||
| US6610285 |
Other References:
J. Biol. Chem., vol. 278, pages 1910-1914 (2003)
Attorney, Agent or Firm:
Kyousei Tamura
Samejima Mutsumi
Masahiro Nitta
Yushiro Tsuboi
Kure Hidenori
Samejima Mutsumi
Masahiro Nitta
Yushiro Tsuboi
Kure Hidenori