本態性振戦症が強化されたマウスモデル及びその製造方法 - KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

Title:

本態性振戦症が強化されたマウスモデル及びその製造方法

Document Type and Number:

Japanese Patent JP5079839

Kind Code:

B2

Abstract:

Disclosed herein are an ± 1/CaV3.1 double knockout mouse or ± 1 -/- ;Emx1-Cre mouse with enhanced essential tremor and a screening method of therapeutic agents for essential tremor by using the same. The ± 1/CaV3.1 double knockout mouse or ± 1 -/- ;Emx1-Cre mouse of the present invention may be usefully used for development of therapeutic agents for essential tremor because the mouse exhibits essential tremor strong and evident enough to be visually confirmed, compared to an ± 1 knockout mouse.

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Inventors:

Kim Tess
Chang Kyon
Park Hyun
Park Young Gyun

Application Number:

JP2010086628A

Publication Date:

November 21, 2012

Filing Date:

April 05, 2010

Export Citation:

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Assignee:

KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

International Classes:

A01K67/027; C12N5/10; G01N33/15; C12N15/09

Other References:

Cerebellum,2007年,Vol.6, No.1,pp.66-72

Attorney, Agent or Firm:

Patent Business Corporation Saegusa International Patent Office

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