Title:
変異型アセチルトランスフェラーゼMpr1
Document Type and Number:
Japanese Patent JP5087775
Kind Code:
B2
Abstract:
The present invention provides a mutant-type acetyltransferase Mpr1: which comprises an amino acid sequence of a yeast wild-type Mpr1 represented by SEQ ID NO:1, wherein at least one amino acid at positions 63 to 65 and 117 of the amino acid sequence is substituted and said mutant-type acetyltransferase Mpr1 exhibits a higher antioxidant capacity than the wild-type Mpr1. The mutant-type acetyltransferase Mpr1 of the present invention exhibits a higher resistance to oxidative stress compared to the wild-type Mpr1. The present invention further provides a gene encoding the mutant-type Mpr1, a vector comprising the gene and a yeast transformed with the gene.
Inventors:
Hiroshi Takagi
Application Number:
JP2008524725A
Publication Date:
December 05, 2012
Filing Date:
February 27, 2007
Export Citation:
Assignee:
Nara Institute of Science and Technology
International Classes:
C12N15/09; C12N1/19; C12N9/10
Other References:
伊井谷薫,高木博史,日本農芸化学会関西支部大会講演要旨集,2006年10月23日,2006年度,第32頁C13
MORITA, Y. et al.,Appl. Environ. Microbiol.,2003年,Vol.69, No.1,pp.212-219
SHICHIRI, M. et al.,J. Biol. Chem.,2001年,Vol.276, No.45,pp.41998-42002
MORITA, Y. et al.,Appl. Environ. Microbiol.,2003年,Vol.69, No.1,pp.212-219
SHICHIRI, M. et al.,J. Biol. Chem.,2001年,Vol.276, No.45,pp.41998-42002
Attorney, Agent or Firm:
Mitsuo Tanaka
Hiroshi Yamazaki
Michiko Matsutani
Mina Shiga
Sakurai Yoko
Satoshi Hashimoto
Hiroshi Yamazaki
Michiko Matsutani
Mina Shiga
Sakurai Yoko
Satoshi Hashimoto