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Title:
3-ピリジルエナンチオマーおよび鎮痛薬としてのその使用
Document Type and Number:
Japanese Patent JP5364872
Kind Code:
B2
Abstract:
The present invention relates to a method of controlling pain in mammals, including humans, comprising administering to a mammal or patient in need of treatment thereof selected compounds of formula (I) or a pharmaceutically acceptable salt thereof. The invention further relates to selected (R) and (S) compounds of formula (I) which are useful as analgesics as well as neuronal cell death preventors and anti-inflammatories.

Inventors:
Marc Davryu Holladay
Stephen P. Arnerick
Hao Bye
Michael Jay Dirt
Nan-Horn Lin
Jiyoung Kay Lynch
Yatto Sun Oh
Keith Bee Ricer
The James P Sullivan
The Ames Tay Washikatsuk
Paul P. Erleitzhi
Application Number:
JP2008327771A
Publication Date:
December 11, 2013
Filing Date:
December 24, 2008
Export Citation:
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Assignee:
AbbVie Incorporated
International Classes:
A61P25/04; A61K31/4427; C07D205/04; A61K31/443; A61K31/4439; A61K31/485; A61P25/28; A61P29/00; C07D401/12; C07D401/14; C07D405/14
Domestic Patent References:
JP4502002A
JP7041475A
Foreign References:
US4620866
Other References:
ABREO,M.A. et al,Novel 3-Pyridyl Ethers with Subnanomolar Affinity for Central Neuronal Nicotinic Acetylcholine Receptors,Journal of Medicinal Chemistry,1996年,Vol.39, No.4,p.817-825
Attorney, Agent or Firm:
Kawaguchi International Patent Office