アデノシンA2A受容体アゴニストとして使用するためのプリン誘導体

Japanese Patent JP5373599

B2

A compound of formula (I) or stereoisomers or pharmaceutically acceptable salts thereof, and their preparation and use as pharmaceuticals wherein R 1 , R 2 and R 3 are as defined herein. The compounds are useful for the treatment of a condition mediated by activation of the adenosine A2A receptor, especially inflammatory or obstructive airways diseases. Pharmaceutical compositions comprising a purine derivative as active ingredient and a process for the preparation of these compounds.

JP3055818	INDUSTRIAL APPLICABILITY: Prinyl and pyrimidinyl tetrahydrofurans
WO/2010/034707	SUBSTITUTED PURINYL-PYRAZOL DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS
JP2006517955	New purine derivatives, methods of their manufacture, pharmaceutical applications, pharmaceutical compositions, and novel uses

Robin Alec Fairhurst
Roger John Taylor
Brian Cox

JP2009505779A

December 18, 2013

April 19, 2007

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Novartis Age

C07D473/16; A61K31/52; A61K31/5377; A61P1/04; A61P1/12; A61P1/16; A61P3/10; A61P7/00; A61P7/06; A61P9/10; A61P9/12; A61P11/00; A61P11/02; A61P13/12; A61P17/00; A61P17/02; A61P17/04; A61P17/06; A61P17/14; A61P19/00; A61P19/02; A61P21/00; A61P21/04; A61P25/00; A61P25/20; A61P27/02; A61P27/06; A61P29/00; A61P37/06; A61P37/08; A61P43/00; C07D495/04; C07D473/34

JP4904279B2
JP2008534447A
JP2004501929A
JP2004508284A
JP2003511460A
JP2003506461A
JP2002501928A
JP2000501694A

Mitsuo Tanaka
Takuji Yamada
Mitsutaka Iwasaki
Aoyama Aoi

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