Title:
抗体-薬物複合体の併用療法
Document Type and Number:
Japanese Patent JP5485897
Kind Code:
B2
Abstract:
Methods for the treatment of Hodgkin's lymphoma comprising administering both a chemotherapeutic regimen and an antibody-drug conjugate compound to a subject in need thereof are provided.
Inventors:
Ofrazol, Ezogerin
Eric Shivers
Gerber, Hans-Peter
Eric Shivers
Gerber, Hans-Peter
Application Number:
JP2010529007A
Publication Date:
May 07, 2014
Filing Date:
October 08, 2008
Export Citation:
Assignee:
Seattle Genetics, Incorporated
International Classes:
A61K31/40; A61K31/407; A61K31/4164; A61K31/7068; A61K39/395; A61K47/48; A61P35/00
Other References:
FRANCISCO,J.A. et al,cAC10-vcMMAE, an anti-CD30-monomethyl auristatin E conjugate with potent and selective antitumor activity,Blood,2003年,Vol.102, No.4,p.1458-65
SCHNELL,R. et al,SGN-30 (Seattle genetics),Curr Opin Mol Ther,2006年,Vol.8, No.2,p.164-72
HEUCK,F. et al,Combination of the human anti-CD30 antibody 5F11 with cytostatic drugs enhances its antitumor activity against Hodgkin and anaplastic large cell lymphoma cell lines,J Immunother,2004年,Vol.27, No.5,p.347-53
BARTLETT,N.L. et al,Gemcitabine, vinorelbine, and pegylated liposomal doxorubicin (GVD), a salvage regimen in relapsed Hodgkin's lymphoma: CALGB 59804,Ann Oncol,2007年,Vol.18, No.6,p.1071-9
BARTLETT,N.L.,Therapies for relapsed Hodgkin lymphoma: transplant and non-transplant approaches including immunotherapy,Hematology Am Soc Hematol Educ Program,2005年,p.245-51
CASHEN,A.F. et al,Therapy of relapsed Hodgkin lymphoma,Blood Rev,2007年,Vol.21, No.5,p.233-43
ANSELL,S.M. et al,Management of Hodgkin lymphoma,Mayo Clin Proc,2006年,Vol.81, No.3,p.419-26
SCHNELL,R. et al,SGN-30 (Seattle genetics),Curr Opin Mol Ther,2006年,Vol.8, No.2,p.164-72
HEUCK,F. et al,Combination of the human anti-CD30 antibody 5F11 with cytostatic drugs enhances its antitumor activity against Hodgkin and anaplastic large cell lymphoma cell lines,J Immunother,2004年,Vol.27, No.5,p.347-53
BARTLETT,N.L. et al,Gemcitabine, vinorelbine, and pegylated liposomal doxorubicin (GVD), a salvage regimen in relapsed Hodgkin's lymphoma: CALGB 59804,Ann Oncol,2007年,Vol.18, No.6,p.1071-9
BARTLETT,N.L.,Therapies for relapsed Hodgkin lymphoma: transplant and non-transplant approaches including immunotherapy,Hematology Am Soc Hematol Educ Program,2005年,p.245-51
CASHEN,A.F. et al,Therapy of relapsed Hodgkin lymphoma,Blood Rev,2007年,Vol.21, No.5,p.233-43
ANSELL,S.M. et al,Management of Hodgkin lymphoma,Mayo Clin Proc,2006年,Vol.81, No.3,p.419-26
Attorney, Agent or Firm:
Yusuke Hiraki
Ishii Teiji
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka
Ishii Teiji
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka