Title:
肝癌治療剤
Document Type and Number:
Japanese Patent JP5506654
Kind Code:
B2
Abstract:
A novel pharmaceutical composition for treating or preventing hepatocellular carcinoma and a method of treatment are provided. A pharmaceutical composition for treating or preventing liver cancer is obtained by combining a chemotherapeutic agent with an anti-glypican 3 antibody. Also disclosed is a pharmaceutical composition for treating or preventing liver cancer which comprises as an active ingredient an anti-glypican 3 antibody for use in combination with a chemotherapeutic agent, or which comprises as an active ingredient a chemotherapeutic agent for use in combination with an anti-glypican 3 antibody. Using the chemotherapeutic agent and the anti-glypican 3 antibody in combination yields better therapeutic effects than using the chemotherapeutic agent alone, and mitigates side effects that arise from liver cancer treatment with the chemotherapeutic agent.
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Inventors:
Kyoko Kinoshita
Masamichi Sugimoto
Takahiro Ishiguro
Masamichi Sugimoto
Takahiro Ishiguro
Application Number:
JP2010291590A
Publication Date:
May 28, 2014
Filing Date:
December 28, 2010
Export Citation:
Assignee:
Chugai Pharmaceutical Co., Ltd.
International Classes:
A61K39/395; A61K31/4045; A61P1/16; A61P35/00; A61P43/00
Domestic Patent References:
| JP2007300927A | ||||
| JP2005508920A | ||||
| JP2006523713A | ||||
| JP2006523457A |
Foreign References:
| WO2007099988A1 |
Other References:
池田公史, 他.,原発性肝がんの薬物療法とキナーゼ阻害剤sorafenib,血液・腫瘍科,日本,科学評論社,2008年 1月28日,Vol.56, No.1,p.70-75,ISSN:0915-8529
Attorney, Agent or Firm:
Seiji Ohno
Koji Morita
Reiko Tanaka
Yuko Matsuniya
Ken Kitano
Natsuki Ito
Koji Morita
Reiko Tanaka
Yuko Matsuniya
Ken Kitano
Natsuki Ito