Title:
S-ニトロソグルタチオンの安定化方法、及び該方法により調製される組成物
Document Type and Number:
Japanese Patent JP5508286
Kind Code:
B2
Abstract:
The invention relates to pharmaceutical compositions having alkaline pH comprising S-nitrosoglutathione (GSNO) as active ingredient together with usual additives, optionally with one or more polysaccharide-type polymer(s). Another subject of the invention is a method for stabilizing a solution or non-solid composition containing GSNO wherein the pH of the solution or composition is adjusted to an alkaline value.
Inventors:
Lazzeza, Jon Boll
Hornique, Istvan
Hornique, Istvan
Application Number:
JP2010542695A
Publication Date:
May 28, 2014
Filing Date:
January 16, 2009
Export Citation:
Assignee:
Pharmagenix Akchen Gezel Shaft
International Classes:
A61K38/00; A61K9/06; A61K9/08; A61K9/19; A61K47/32; A61K47/34; A61K47/36; A61P9/08; A61P17/02; A61P21/00; A61P25/02
Foreign References:
US20020002136 |
Other References:
PHOTOCHEMISTRY AND PHOTOBIOLOGY,1998,Vol. 67,No. 3,p.282-288
NITRIC OXIDE,2000,Vol.4,No.1,p.57-66
INDUSTRIE ALIMENTARI,1975,Vol.14,No.7-8,p.79-81
JOURNAL OF PHARMACEUTICAL SCIENCES,2005,Vol.95,N.5,p.994-1003
NITRIC OXIDE,2000,Vol.4,No.1,p.57-66
INDUSTRIE ALIMENTARI,1975,Vol.14,No.7-8,p.79-81
JOURNAL OF PHARMACEUTICAL SCIENCES,2005,Vol.95,N.5,p.994-1003
Attorney, Agent or Firm:
Asamura patent office
Hideto Asamura
Hajime Asamura
Yoshitaka Watanabe
Naganuma Akio
Yukihiro Ikeda
Kajiwara Saiko
Shinmura Morio
Kanamori Koji
Yuko Nagase
Youichi Inoue
Mari Yuge
Katsuhiko Shimomura
Hideto Asamura
Hajime Asamura
Yoshitaka Watanabe
Naganuma Akio
Yukihiro Ikeda
Kajiwara Saiko
Shinmura Morio
Kanamori Koji
Yuko Nagase
Youichi Inoue
Mari Yuge
Katsuhiko Shimomura