医薬化合物 - Genentech and in condominium lei テッド

Title:

医薬化合物

Document Type and Number:

Japanese Patent JP5546240

Kind Code:

B2

Abstract:

Compounds of Formulae la and Ib, and stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting lipid kinases including PI3K, and for treating disorders such as cancer mediated by lipid kinases. Methods of using compounds of Formula la and Ib for in vitro , in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.

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Inventors:

The Volks, Adrian
Shuttle ワース, Stephen
チュコウリー, Irina
Oxen Ford, a sari
One, nan Chee
Caster ネード, georgette
Cancer ズナー, Janet
It passes and they are chlorofluocarbon and Tim.
Matthew, Simon
Olivero, Alan
サザーリン, Daniel, Py.
Chu, ビンーヤン
Goldsmith, Richard

Application Number:

JP2009507751A

Publication Date:

July 09, 2014

Filing Date:

April 24, 2007

Export Citation:

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Assignee:

Genentech and in condominium lei テッド
F. Hoffmann * ラ Roche アーゲー F. HOFFMANN*LA ROCHE AKTIENGESELLSCHAFT

International Classes:

C07D495/04; A61K31/5377; A61K45/00; A61P3/00; A61P5/00; A61P9/00; A61P25/00; A61P29/00; A61P31/12; A61P35/00; A61P35/02; A61P37/02; A61P43/00; C07D491/048; C07D519/00; C07B61/00

Attorney, Agent or Firm:

Kobayashi 浩
Eiji Katayama
Norio Omori
Yasuhito Suzuki

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