Title:
カッパオピオイド受容体リガンド
Document Type and Number:
Japanese Patent JP5571133
Kind Code:
B2
Abstract:
Kappa opioid receptor antagonists are provided that yield significant improvements in functional binding assays to kappa opioid receptors, and the use of these antagonists in treatment of disease states that are ameliorated by binding of the kappa opioid receptor such as heroin or cocaine addictions.
Inventors:
Frank Ivy Carol
The Herman Ey ナヴァロ
Lawrence E Brie Addie
Scott Py Runyon
James B Thomas
The Herman Ey ナヴァロ
Lawrence E Brie Addie
Scott Py Runyon
James B Thomas
Application Number:
JP2012158446A
Publication Date:
August 13, 2014
Filing Date:
July 17, 2012
Export Citation:
Assignee:
Research triangle institute
International Classes:
C07D405/12; A61K31/453; A61K31/4535; A61P1/12; A61P3/04; A61P9/12; A61P11/14; A61P13/00; A61P19/02; A61P25/00; A61P25/04; A61P25/06; A61P25/16; A61P25/18; A61P25/24; A61P25/30; A61P25/32; A61P25/36; A61P31/12; A61P37/02; A61P37/06; A61P37/08; A61P43/00; C07D409/12
Attorney, Agent or Firm:
Yasuhiko Murayama
Masatake Shiga
Takashi Watanabe
Shinya Jitsuhiro
Masatake Shiga
Takashi Watanabe
Shinya Jitsuhiro