Ｐ３８キナーゼ阻害剤 - メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋＳｈａｒｐ＆ＤｏｈｍｅＣｏｒｐ．

Title:

Ｐ３８キナーゼ阻害剤

Document Type and Number:

Japanese Patent JP5620979

Kind Code:

B2

Abstract:

Compounds described by the chemical formula (I) or pharmaceutically acceptable salts thereof: Formula (I); are inhibitors of p38 and are useful in the treatment of inflammation such as in the treatment of asthma, COPD, ARDS, rheumatoid arthritis, rheumatoid spondylitis, osteoarthritis, gouty arthritis and other arthritic conditions; inflamed joints, eczema, psoriasis or other inflammatory skin conditions such as sunburn; inflammatory eye conditions including conjunctivitis; pyresis, pain and other conditions associated with inflammation.

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Inventors:

小山裕雄
サホー，スーミヤ・ピー
ヤン，ジンジヤー・シユ−チアン
ミラー，ダニエル・ジエイ

Application Number:

JP2012509832A

Publication Date:

November 05, 2014

Filing Date:

April 26, 2010

Export Citation:

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Assignee:

メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋＳｈａｒｐ＆ＤｏｈｍｅＣｏｒｐ．

International Classes:

C07D417/12; A61K31/433; A61K31/4439; A61K31/497; A61K31/519; A61P11/00; A61P11/06; A61P19/02; A61P19/06; A61P29/00; C07D417/14; C07D487/04

Attorney, Agent or Firm:

Iwase Yoshiwa
Makoto Ono
Yoshinori Kanayama
Michiaki Tsubokura
Kazuteru Shigemori
Yasufumi Shiroyama

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