Title:
治療剤配送のためのシクロデキストリン基材重合体
Document Type and Number:
Japanese Patent JP5681646
Kind Code:
B2
Abstract:
The present invention relates to novel compositions of therapeutic cyclodextrin containing polymeric compounds designed as a carrier for small molecule therapeutics delivery and pharmaceutical compositions thereof. These cyclodextrin-containing polymers improve drug stability and solubility, and reduce toxicity of the small molecule therapeutic when used in vivo. Furthermore, by selecting from a variety of linker groups and targeting ligands the polymers present methods for controlled delivery of the therapeutic agents. The invention also relates to methods of treating subjects with the therapeutic compositions described herein. The invention further relates to methods for conducting pharmaceutical business comprising manufacturing, licensing, or distributing kits containing or relating to the polymeric compounds described herein.
Inventors:
チャン ジアンジュン
マーク イー．デイビス
ケイ ティー．キン
マーク イー．デイビス
ケイ ティー．キン
Application Number:
JP2012004159A
Publication Date:
March 11, 2015
Filing Date:
January 12, 2012
Export Citation:
Assignee:
セルリアン・ファーマ・インコーポレイテッド
International Classes:
C08B37/16; A61K31/724; A61K47/48; A61P35/00; C08G63/48; C08G63/91
Attorney, Agent or Firm:
Shusaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita