Title:
ＨＭＧ−ＣｏＡ還元酵素由来のペプチド、および、前記ペプチドを含む美容または医薬組成物
Document Type and Number:
Japanese Patent JP5694189
Kind Code:
B2
Abstract:
The present invention relates to a peptide of general formula (I): R1-(AA)n-X1-Gly-Glu-Leu-Ser-X2-X3-(AA)p-R2, derived from human HMG-CoA reductase. The present invention also relates to a cosmetic or pharmaceutical composition comprising at least one peptide of general formula (I), in a physiologically suitable medium. The present invention further relates to the use of this novel peptide as an active principle that activates human HMG-CoA reductase in a cosmetic composition intended to strengthen the barrier function of the skin and to stimulate epidermal differentiation. The invention further applies to a cosmetic treatment method intended to prevent and/or combat the external stresses and signs of cutaneous aging.
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Inventors:
Claude d'Alfalla
Noua Domroje
Jean-Mari Bot
Noua Domroje
Jean-Mari Bot
Application Number:
JP2011542862A
Publication Date:
April 01, 2015
Filing Date:
December 23, 2009
Export Citation:
Assignee:
ISPE Investments, Inc.
International Classes:
C07K7/06; A61K8/64; A61K38/44; A61P17/00; A61P17/16; A61P29/00; A61P37/08; A61P43/00; A61Q19/00; A61Q19/08
Domestic Patent References:
| JP2007534307A |
Foreign References:
| WO2005080985A1 | ||||
| WO2003023067A1 | ||||
| WO2003087831A1 |
Attorney, Agent or Firm:
Yasuhiko Murayama
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro