Title:
ＡＴＰ結合カセットトランスポーターのモジュレーター
Document Type and Number:
Japanese Patent JP5712117
Kind Code:
B2
Abstract:
The present invention relates to modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, composition thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
Inventors:
Sarah S. Hadi Da Lua
Anna Earle. Hazlewood
Peter Dee Jay Jay Gruttenhuy
Frederick F. Van Goor
Ashbani K. Shin
Jinlan butterfly
Jason McCartney
Anna Earle. Hazlewood
Peter Dee Jay Jay Gruttenhuy
Frederick F. Van Goor
Ashbani K. Shin
Jinlan butterfly
Jason McCartney
Application Number:
JP2011266327A
Publication Date:
May 07, 2015
Filing Date:
December 05, 2011
Export Citation:
Assignee:
VERTEX PHARMACEUTICALS INCORPORATED
International Classes:
C07D209/08; C07D401/12
Domestic Patent References:
| JP2001199965A | ||||
| JP2000256358A | ||||
| JP2138260A | ||||
| JP58018361A | ||||
| JP2001502683A | ||||
| JP55081878A | ||||
| JP11513021A | ||||
| JP6509061A | ||||
| JP3193725A |
Foreign References:
| US3524858 | ||||
| WO2005094805A1 | ||||
| WO2002078693A1 |
Other References:
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I.M. HEILBRONN, et al.,JOURNAL OF THE CHEMICAL SOCIETY,1928年,p.934-941
K. GROHE, et al.,LIEBIGS ANNALEN DER CHEMIE,1987年,p.871-879
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F. CLEMENCE, et al.,JOURNAL OF MEDICINAL CHEMISTRY,1988年,Vol.31,No.7,p.1453-1462
R. M. ROBERTS, et al.,JOURNAL OF ORGANIC CHEMISTRY,1949年,Vol.14,p.277-284
R. K. BROWN,et al.,JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,1955年,Vol.77,p.3839-3842
B. HESTER,et al.,JOURNAL OF MEDICINAL CHEMISTRY,1964年,Vol.7,No.3,p.274-279
T. G. MURALI DHAR, et al.,BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2003年,Vol.13,p.3557-3560
K. IRIE,et al.,TETRAHEDRON,1995年,Vol.51,No.22,p.6255-6266
E. W. MILES,et al.,BIOCHEMISTRY,1985年,Vol.24,No.17,p.4694-4703
A. H. MANDOUR,et al.,EGYPTIAN JOURNAL OF CHEMISTRY,1999年,Vol.42,No.3,p.251-266
R. K. BROWN,et al.,JOURNAL OF ORGANIC CHEMISTRY,1956年,Vol.21,p.261-262
G. SETTIM,et al.,JOURNAL OF HETEROCYCLIC CHEMISTRY,1988年,Vol.25,No.5,p.1391-1397
T. IMANISHI, et al.,NEUROPHARMACOLOGY,1996年,Vol.35,No.9/10,p.1271-1277
H. KURATA, et al.,BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS,2004年,Vol.14,p.1183-1186
T. VAN ES, et al.,SOUTH AFRICAN JOURNAL OF CHEMISTRY,2001年,Vol.54,p.102-117
I.M. HEILBRONN, et al.,JOURNAL OF THE CHEMICAL SOCIETY,1928年,p.934-941
K. GROHE, et al.,LIEBIGS ANNALEN DER CHEMIE,1987年,p.871-879
D. KAMINSKY, et al.,JOURNAL OF MEDICINAL CHEMISTRY,1968年,Vol.11,No.1,p.160-163
F. CLEMENCE, et al.,JOURNAL OF MEDICINAL CHEMISTRY,1988年,Vol.31,No.7,p.1453-1462
R. M. ROBERTS, et al.,JOURNAL OF ORGANIC CHEMISTRY,1949年,Vol.14,p.277-284
R. K. BROWN,et al.,JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,1955年,Vol.77,p.3839-3842
B. HESTER,et al.,JOURNAL OF MEDICINAL CHEMISTRY,1964年,Vol.7,No.3,p.274-279
T. G. MURALI DHAR, et al.,BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2003年,Vol.13,p.3557-3560
K. IRIE,et al.,TETRAHEDRON,1995年,Vol.51,No.22,p.6255-6266
E. W. MILES,et al.,BIOCHEMISTRY,1985年,Vol.24,No.17,p.4694-4703
A. H. MANDOUR,et al.,EGYPTIAN JOURNAL OF CHEMISTRY,1999年,Vol.42,No.3,p.251-266
R. K. BROWN,et al.,JOURNAL OF ORGANIC CHEMISTRY,1956年,Vol.21,p.261-262
G. SETTIM,et al.,JOURNAL OF HETEROCYCLIC CHEMISTRY,1988年,Vol.25,No.5,p.1391-1397
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita