Title:
グルコースの吸収および排泄の指標としてのα−メチルグルコシド（ＡＭＧ）の使用
Document Type and Number:
Japanese Patent JP5722901
Kind Code:
B2
Abstract:
Presented here are methods using alpha-methylglucoside (AMG) in vivo as an indicator for glucose absorption from the gastrointestinal (GI) system or glucose excretion in the urine after oral administration of AMG. The methods find use in, for example, but not limited to, determining the effect of a sodium-dependent glucose transporter (SGLT) inhibitor in an animal, comparing the differences in the effects of a first and second SGLT inhibitor in an animal, and diagnosing a disease associated with glucose absorption from the gastrointestinal (GI) system or glucose excretion from the kidney in an animal.
Inventors:
Demarest, Keith Tay
Leonard, The Ames M
Leo, Gregory Sea
Liang, Inn
Martain, Tonia El
Leonard, The Ames M
Leo, Gregory Sea
Liang, Inn
Martain, Tonia El
Application Number:
JP2012529847A
Publication Date:
May 27, 2015
Filing Date:
September 14, 2010
Export Citation:
Assignee:
JANSSEN PHARMACEUTICA NAAMLOZE VENNOOTSCHAP
International Classes:
G01N33/66; A61K49/00
Domestic Patent References:
| JP2008528441A | ||||
| JP2005015460A | ||||
| JP4540475B2 | ||||
| JP2006521562A | ||||
| JP2009155212A |
Foreign References:
| WO2005044290A1 |
Attorney, Agent or Firm:
Patent business corporation Odashima patent office