Title:
治療薬を送達するための新規な脂質及び組成物
Document Type and Number:
Japanese Patent JP5747282
Kind Code:
B2
Abstract:
The present invention provides lipids that are advantageously used in lipid particles for the in vivo delivery of therapeutic agents to cells.
Inventors:
Mutiah Manoharan
Callantottil, Gee Rajiv
David Butler
Jayapurakash Kah Narayana Nile
Muthu Sammy Jayaraman
Luxman Eltep
Callantottil, Gee Rajiv
David Butler
Jayapurakash Kah Narayana Nile
Muthu Sammy Jayaraman
Luxman Eltep
Application Number:
JP2011535779A
Publication Date:
July 15, 2015
Filing Date:
November 10, 2009
Export Citation:
Assignee:
Tekmira Pharmaceuticals Corporation
International Classes:
C07D317/28; A61K9/14; A61K31/7088; A61K39/00; A61K39/002; A61K39/012; A61K39/02; A61K47/24; A61K47/28; A61K47/34; A61K48/00; A61P35/00; C07D317/34; C07D317/44; C07D317/58; C07D317/66; C07D317/72; C07D491/056
Other References:
Chem.Commun.,2008年,(43),pp.5550-5552
J.Am.Chem.Soc.,2008年,130(44),pp.14454-14455
J.Org.Chem.,2007年,72(8),pp.3155-3157
J.Org.Chem.,2007年,72(17),pp.6591-6594
J.Am.Chem.Soc.,1998年,120(16),pp.4017-4018
J.Am.Chem.Soc.,2004年,126(1),pp.187-193
J.Am.Chem.Soc.,2008年,130(44),pp.14454-14455
J.Org.Chem.,2007年,72(8),pp.3155-3157
J.Org.Chem.,2007年,72(17),pp.6591-6594
J.Am.Chem.Soc.,1998年,120(16),pp.4017-4018
J.Am.Chem.Soc.,2004年,126(1),pp.187-193
Attorney, Agent or Firm:
Yasuhiko Murayama
Shinya Mitsuhiro
Tatsuhiko Abe
Shinya Mitsuhiro
Tatsuhiko Abe