Title:
キメラ抗体および処置におけるその使用
Document Type and Number:
Japanese Patent JP5781571
Kind Code:
B2
Abstract:
Disclosed are surprising discoveries concerning the role of anionic phospholipids and aminophospholipids in tumor vasculature and in viral entry and spread, and compositions and methods for utilizing these findings in the treatment of cancer and viral infections. Also disclosed are advantageous antibody, immunoconjugate and duramycin-based compositions and combinations that bind and inhibit anionic phospholipids and aminophospholipids, for use in the safe and effective treatment of cancer, viral infections and related diseases.
Inventors:
Philip E. Soap
Melina M. Thor
Shan Min Juan
Hee Jin
Sophia Run
Melina M. Thor
Shan Min Juan
Hee Jin
Sophia Run
Application Number:
JP2013165247A
Publication Date:
September 24, 2015
Filing Date:
August 08, 2013
Export Citation:
Assignee:
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
International Classes:
A61K45/00; C07K16/30; A61K9/127; A61K39/395; A61K47/48; A61P3/04; A61P3/10; A61P5/14; A61P5/16; A61P7/04; A61P7/06; A61P9/00; A61P9/10; A61P15/08; A61P17/00; A61P17/06; A61P17/10; A61P19/02; A61P19/06; A61P27/02; A61P27/06; A61P29/00; A61P31/10; A61P31/12; A61P31/22; A61P33/00; A61P35/00; A61P37/02; A61P43/00; C07K16/18; C07K16/28; C07K16/44; C07K16/46
Domestic Patent References:
| JP2011213737A | ||||
| JP2002520295A | ||||
| JP2002520297A |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Natsuki Morishita