Title:
神経細胞への分化誘導培地、および、神経細胞への分化誘導方法
Document Type and Number:
Japanese Patent JP5823925
Kind Code:
B2
Abstract:
The present invention discloses a neural induction medium comprising Wnt-signal agonist, TGFbeta-signal inhibitor and FGF-signal agonist for inducing neural differentiation. The neural induction medium used in a culture system is capable for inducing the neural differentiation of stem cells into neuroepithelial cells which are useful for the clinical applications. Therein, the neuroepithelial cells can further differentiate into mature neurons for the practical applications including regeneration medicine and drug discovery for neural disorders.
Inventors:
Su Rin
Chen Seimi
Chen Seimi
Application Number:
JP2012139022A
Publication Date:
November 25, 2015
Filing Date:
June 20, 2012
Export Citation:
Assignee:
National Chungking University
International Classes:
C12N5/0793; C12N5/10
Foreign References:
| WO2011055899A1 | ||||
| WO2005123902A1 | ||||
| WO2011019092A1 |
Other References:
ZHANG, S.C., et al.,Nature Biotech.,2001年12月,19,pp.1129-1133
平林祐介ら,第27回日本分子生物学会年会プログラム・講演要旨集,2004年,p.368(要旨番号W2Q-5)
SATO, N., et al.,Nature Medicine,2004年 1月,10(1),pp.55-63
菊地哲広ら,浮遊培養法によるヒトES及びiPS細胞からの神経分化誘導,再生医療,2010年,9(Suppl.),,p.163(抄録番号O-05-1)
平林祐介ら,第27回日本分子生物学会年会プログラム・講演要旨集,2004年,p.368(要旨番号W2Q-5)
SATO, N., et al.,Nature Medicine,2004年 1月,10(1),pp.55-63
菊地哲広ら,浮遊培養法によるヒトES及びiPS細胞からの神経分化誘導,再生医療,2010年,9(Suppl.),,p.163(抄録番号O-05-1)
Attorney, Agent or Firm:
Masaki Hattori
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