Title:
骨再生のためのエリスロポイエチンおよびフィブロネクチン組成物
Document Type and Number:
Japanese Patent JP5829400
Kind Code:
B2
Abstract:
A method of promoting bone regeneration in a subject in need thereof is disclosed. The method comprising administering to the subject a therapeutically effective amount of Erythropoietin and Fibronectin, thereby promoting bone regeneration in the subject, (i) wherein the therapeutically effective amount of the Erythropoietin is selected from the group consisting of: about 1-50 mg/Kg for systemic administration; and about 0.1-50 mg/ml for local administration, and (ii) wherein the therapeutically effective amount of the Fibronectin is selected from the group consisting of: about 100-1000 mg/ml for systemic administration; and about 50-500 mg/ml for local administration.
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Inventors:
Hamed, Sahel
Application Number:
JP2010543624A
Publication Date:
December 09, 2015
Filing Date:
January 22, 2009
Export Citation:
Assignee:
Remede Biomed Limited
International Classes:
A61K38/22; A61K38/16; A61L27/00; A61P19/08; A61P43/00
Domestic Patent References:
| JP2007517001A |
Foreign References:
| DE10303584A1 |
Other References:
PHAM,M.T. et al,Journal of biomedical materials research. Part A,2003年,Vol.66, No.2,p.310-6
SOUMETZ,F.C. et al,Journal of biomedical materials research. Part B, Applied biomaterials,2007年,Vol.84, No.1,p.249-55
神保良 他,血清ファイブロネクチンのオッセオインテグレーション促進効果,日本口腔インプラント学会誌,2007年,Vol.20, No.1,p.82-83
武部純 他,岩手医科大学歯学雑誌,2001年,Vol.26, No.2,p.61-76
SOUMETZ,F.C. et al,Journal of biomedical materials research. Part B, Applied biomaterials,2007年,Vol.84, No.1,p.249-55
神保良 他,血清ファイブロネクチンのオッセオインテグレーション促進効果,日本口腔インプラント学会誌,2007年,Vol.20, No.1,p.82-83
武部純 他,岩手医科大学歯学雑誌,2001年,Vol.26, No.2,p.61-76
Attorney, Agent or Firm:
Patent business corporation r&c