Title:
第ＸＩＡ因子阻害剤としてのマクロ環
Document Type and Number:
Japanese Patent JP5841547
Kind Code:
B2
Abstract:
The present invention provides synthetic intermediates useful in the preparation of compounds of Formula (I) or a stereoisomer, a tautomer, or a pharmaceutically acceptable salt thereof, wherein all the variables are as defined herein. These compounds are selective Factor Xia inhibitors or dual inhibitors of fXIa and plasma kallikrein.
Inventors:
Mimi El Kwan
Karl P. Decicco
James Earl Court
One Kairan
Karl P. Decicco
James Earl Court
One Kairan
Application Number:
JP2012552985A
Publication Date:
January 13, 2016
Filing Date:
February 10, 2011
Export Citation:
Assignee:
BRISTOL-MYERS SQUIBB COMPANY
International Classes:
C07D471/08; C07D471/18; C07D487/08; C07D487/18; C07D498/08; C07D498/18
Domestic Patent References:
| JP2013519678A | ||||
| JP2001517671A | ||||
| JP2008502700A | ||||
| JP2009519966A | ||||
| JP2009519967A |
Foreign References:
| WO2008079836A1 | ||||
| WO2009114677A1 |
Attorney, Agent or Firm:
Kyousei Tamura
Samejima Mutsumi
Nagatoshi Shinagawa
Yasushi Morimoto
Samejima Mutsumi
Nagatoshi Shinagawa
Yasushi Morimoto