Title:
修飾されたプレ‐プロ領域を有するプロテアーゼ
Document Type and Number:
Japanese Patent JP5852568
Kind Code:
B2
Abstract:
The invention relates to modified polynucleotides encoding modified proteases, and methods for altering the production of proteases in microorganisms. In particular, the modified polynucleotides comprise one or more mutations that encode modified proteases having modifications of the pre-pro region that enhance the production of the active enzyme. The present invention further relates to methods for altering the production of proteases in microorganisms, such as Bacillus species.
Inventors:
Pisa Chic, Alexander
Schmidt, Brian Ef
Schmidt, Brian Ef
Application Number:
JP2012522827A
Publication Date:
February 03, 2016
Filing Date:
April 15, 2010
Export Citation:
Assignee:
Danisco US Inc.
International Classes:
C12N15/09; C12N1/21; C12N9/54; C12N9/56
Domestic Patent References:
| JP2005531307A | ||||
| JP2004187669A |
Foreign References:
| WO2008153934A1 |
Other References:
Biochemistry,1994年,Vol.33,pp.562-569
Attorney, Agent or Firm:
Yuzo Yamazaki
Toshiaki Akamatsu
Ono Wataru
Okuko Masako
Tadao Naito
Takeko Miko
Chihiro Imai
Kei Kiuchi
Hiroaki Nishimura
Toshiaki Akamatsu
Ono Wataru
Okuko Masako
Tadao Naito
Takeko Miko
Chihiro Imai
Kei Kiuchi
Hiroaki Nishimura