Title:
ヘプシジンの吸着用の吸着剤
Document Type and Number:
Japanese Patent JP5898615
Kind Code:
B2
Abstract:
The invention relates to a device and a method for depletion of hepcidin from blood for treatment of iron deficiency, in particular in anemic patients suffering from chronic renal failure, with the goal of increasing the availability of iron in the body and thus improving the treatment of the anemia. The hepcidin adsorbent comprises a matrix and a hepcidin-binding ligand covalently bonded to the matrix with an affinity having a dissociation constant KD of less than 200 nM.
Inventors:
Paslick-Dating Yen Yutta
Hoffman Wolfgang
Hoffman Wolfgang
Application Number:
JP2012520933A
Publication Date:
April 06, 2016
Filing Date:
July 15, 2010
Export Citation:
Assignee:
Fresenius Medical Care Deutsche Land Gesellschaft Mitt Beschlenktel Haftung
International Classes:
A61M1/02; C07K16/26; C07K16/46
Domestic Patent References:
| JP56145858A | ||||
| JP58097366A | ||||
| JP2006517198A |
Foreign References:
| US20080213277 | ||||
| WO2009044284A1 | ||||
| WO2009058797A1 | ||||
| US20070224186 |
Other References:
Peslova et al.,BLOOD,2009年 6月,Vol.113, No.24,P.6225-6236
Attorney, Agent or Firm:
Takaki Nishijima
Disciple Maru Ken
Shinichiro Tanaka
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Takamitsu Hoshino
Disciple Maru Ken
Shinichiro Tanaka
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Takamitsu Hoshino