Title:
二光子光増感剤、それらを含むナノ粒子および薬物としてのそれらの使用
Document Type and Number:
Japanese Patent JP5926685
Kind Code:
B2
Abstract:
The invention relates to compounds of formula (I) wherein the groups A and B represent independently from each other —CH═CH—, or —C≡C—, the terms t, u, v, w represent, independently from each other, values ranging from 0 to 9, the groups Y1 and Y2 can represent independently from each other an alkyl group (linear, branched or substituted) carrying from 1 to 9 carbon atoms, the groups Z1, Z2, Z3, and Z4 can represent independently from each other a chemically reactive group W, such as OH, NH2, SH, the groups Z5 and Z6 represent independently from each other a hydrogen atom, silica nanoparticles functionalized by these compounds, and their use as drugs.
Inventors:
Brevet, David
Lame, lawrence
Blanchard-Desse, Mireille
Monzine, Olivier
Gary-Bobo-Sable-Teshan, Magari
Garcia, marcel
Morele, Align
Duran, Jean-Olivier
Lame, lawrence
Blanchard-Desse, Mireille
Monzine, Olivier
Gary-Bobo-Sable-Teshan, Magari
Garcia, marcel
Morele, Align
Duran, Jean-Olivier
Application Number:
JP2012543599A
Publication Date:
May 25, 2016
Filing Date:
December 07, 2010
Export Citation:
Assignee:
ECOLE NORMALE SUPERIEURE
Universited Train 1
Institut National De La Sante & De La Recherche Medical
Universited Train 1
Institut National De La Sante & De La Recherche Medical
International Classes:
C07D333/20; A61K31/381; A61K47/48; A61K49/00; A61P35/00; C07D519/00; C07F7/18
Domestic Patent References:
| JP2006516627A |
Foreign References:
| WO2008030624A1 |
Other References:
MONGIN O.,SYNTHESIS, FLUORESCENCE, AND TWO-PHOTON ABSORPTION OF A SERIES OF ELONGATED RODLIKE 以下備考,CHEM. EUR. J.,2007年,V13,P1481-1498,AND BANANA-SHAPED QUADRUPOLAR FLUOROPHORES: A COMPREHENSIVE STUDY OF STRUCTURE-PROPERTY
OHULCHANSKYY T.Y.,ORGANICALLY MODIFIED SILICA NANOPARTICLES WITH COVALENTLY 以下備考,NANO LETTERS,米国,ACS,2007年 1月 1日,V7 N9,P2835-2842,INCORPORATED PHOTOSENSITIZER FOR PHOTODYNAMIC THERAPY OF CANCER
Chem.Commun.,2009年 2月18日,12,p.1475-1477
J. Amer.Chem.Soc,2003年,125,p.7860-7865
OHULCHANSKYY T.Y.,ORGANICALLY MODIFIED SILICA NANOPARTICLES WITH COVALENTLY 以下備考,NANO LETTERS,米国,ACS,2007年 1月 1日,V7 N9,P2835-2842,INCORPORATED PHOTOSENSITIZER FOR PHOTODYNAMIC THERAPY OF CANCER
Chem.Commun.,2009年 2月18日,12,p.1475-1477
J. Amer.Chem.Soc,2003年,125,p.7860-7865
Attorney, Agent or Firm:
Shintaro Nogawa
Shinji Kai
Yusuke Kaneko
Kiyoshi Inamoto
Shinji Kai
Yusuke Kaneko
Kiyoshi Inamoto