Title:
心不全の治療法
Document Type and Number:
Japanese Patent JP6441818
Kind Code:
B2
Abstract:
The present invention relates to the discovery that the administration of nitrate is an effective therapy for improving short-term and long-term outcomes in patients with heart failure, including heart failure with preserved ejection fraction (HFpEF). Thus, the present invention provides compositions and methods for the treatment or prevention of heart failure, including HFpEF, in a subject in need thereof.
Inventors:
Julio A. Chilenos
Application Number:
JP2015557120A
Publication Date:
December 19, 2018
Filing Date:
February 07, 2014
Export Citation:
Assignee:
AstraZeneca UK Limited
International Classes:
A61K33/00; A61K9/08; A61K36/21; A61K45/00; A61P9/04
Domestic Patent References:
| JP2007528852A | ||||
| JP2010519336A |
Foreign References:
| WO2012076667A1 |
Other References:
Dietary Nitrates for Heart Failure: Clinical Trials.gov,2012年12月19日,URL,https://clinicaltrials.gov/archive/NCT01682356/2012_12_19
The journal of physiology,2012年,Vol.591,Issue 2,p.547-557
The journal of physiology,2012年,Vol.591,Issue 2,p.547-557
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Ryotaro Takei
Kazumi Nakamura
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Ryotaro Takei
Kazumi Nakamura