Title:
志賀毒素Aサブユニットエフェクター領域を含む多価CD20結合分子及びそれらの強化組成物
Document Type and Number:
Japanese Patent JP6444486
Kind Code:
B2
Abstract:
Provided herein are multivalent CD20-binding molecules, and compositions thereof, for use in selective killing of specific cell types and/or as therapeutics for the treatment of a variety of diseases, including cancer, tumors, and immune disorders. Certain multivalent CD20-binding molecules can be used to deliver agents into CD20-expressing cells, collecting diagnostic information, and/or monitoring the treatment of diseases, such as cancers, tumors, and immune disorders.
Inventors:
Poma Eric
Willat Erin
Kim jason
Higgins Jack
Liu Jing Sing
Flores-Leffran Rodney
Willat Erin
Kim jason
Higgins Jack
Liu Jing Sing
Flores-Leffran Rodney
Application Number:
JP2017501668A
Publication Date:
December 26, 2018
Filing Date:
February 04, 2016
Export Citation:
Assignee:
MOLECULAR TEMPLATES, INC.
International Classes:
C07K16/28; A61K38/02; A61K39/395; A61K47/02; A61K47/10; A61K47/12; A61K47/14; A61K47/20; A61K47/22; A61K47/24; A61K47/26; A61K47/36; A61K47/42; A61K47/68; A61P1/04; A61P3/10; A61P5/14; A61P11/06; A61P17/00; A61P17/06; A61P19/02; A61P25/00; A61P27/02; A61P29/00; A61P31/04; A61P31/18; A61P35/00; A61P35/02; A61P37/02; A61P37/06; C07K16/46
Domestic Patent References:
JP2003531588A | ||||
JP2002544173A |
Foreign References:
WO2014164693A1 | ||||
WO2014164680A1 |
Attorney, Agent or Firm:
Masaki Hirota
Seiji Ozawa
Yusaku Tokai
Kazuhiro Matsuda
Yasunori Matsuhashi
Makoto Horiuchi
Masako Yamauchi
Shuichi Sonomoto
Akihiro Yamamura
Hiroyuki Tomita
Seiji Ozawa
Yusaku Tokai
Kazuhiro Matsuda
Yasunori Matsuhashi
Makoto Horiuchi
Masako Yamauchi
Shuichi Sonomoto
Akihiro Yamamura
Hiroyuki Tomita
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