Title:
磁性細胞外マトリックス
Document Type and Number:
Japanese Patent JP6466323
Kind Code:
B2
Abstract:
Methods of making and using a magnetic ECM are disclosed. The ECM comprises positively and negatively charged nanoparticles, wherein one of said nanoparticles contains a magnetically responsive element. When the magnetic ECM is seeded with cells, the cells will be magnetized and can be levitated for 3-D cell culture.
Inventors:
Souza, Grauco, Earl
Application Number:
JP2015517365A
Publication Date:
February 06, 2019
Filing Date:
June 11, 2013
Export Citation:
Assignee:
Greiner Bio-One North America, Inc.
International Classes:
C12P1/00; A61K35/12; A61K35/32; A61K35/33; A61K35/36; A61K35/545; A61L27/36; A61L27/54; A61P43/00
Domestic Patent References:
| JP2012503492A |
Foreign References:
| US20070027460 | ||||
| WO2011038370A1 |
Other References:
SOUZA Glauco R., et al.,Three-dimensional tissue culture based on magnetic cell levitation,Nat Nanotechnology,2010年 4月,Vol.5 No.4,Page.291-296
Hongxu Lu, et al.,Comparison of decellularization techniques for preparation of extracellular matrix scaffolds derived from three-dimensional cell culture,Society for Biomaterials,2012年 5月24日,p.2507-2516
Hongxu Lu, et al.,Comparison of decellularization techniques for preparation of extracellular matrix scaffolds derived from three-dimensional cell culture,Society for Biomaterials,2012年 5月24日,p.2507-2516
Attorney, Agent or Firm:
Tadashige Ito
Tadahiko Ito
Shinsuke Onuki
Tadahiko Ito
Shinsuke Onuki