Title:
プロスタグランジンアミドの新規製造方法
Document Type and Number:
Japanese Patent JP6487410
Kind Code:
B2
Abstract:
The subject of the invention is process for the preparation of the prostaglandin amides of the general formula I, where in the formula the bonds marked with dotted lines may be single or double bonds, in the case of double bounds at positions 5,6 and 13,14 they may be in cis or in trans orientation, Q stands for a hydroxyl-group and Z stands for a hydroxyl- or oxo-group, R1 and R2 independently represent hydrogen atom or a straight or branched C1-10 alkyl- or aralkyl-group, optionally substituted with —ONO2 group, or an aralkyl- or aryl-group, which contains heteroatom, R3 represents a straight or branched, saturated or unsaturated C4-6 hydrocarbon group, or a C4-10 alkylcycloalkyl- or cycloalkyl-group, or an optionally with alkyl group or halogen atom substituted phenyl-, C7-10 alkylaryl- or hetaryl-group, Y represents (CH2)n group or O atom or S atom, and where n=0-3.
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Inventors:
Habashi, Gabor
Kitsushiyu, Tabor
Holtberg, Elaine
Cardosyu, Jiujianjina
Lars Lohuy, Ishiyutburn
Bishyukov, Zoltan
Bodecheille, Arderm
Kitsushiyu, Tabor
Holtberg, Elaine
Cardosyu, Jiujianjina
Lars Lohuy, Ishiyutburn
Bishyukov, Zoltan
Bodecheille, Arderm
Application Number:
JP2016234693A
Publication Date:
March 20, 2019
Filing Date:
December 02, 2016
Export Citation:
Assignee:
Quinoin See El Tee
International Classes:
C07C405/00
Domestic Patent References:
| JP2004529973A |
Foreign References:
| US20090163596 | ||||
| WO2009153206A1 | ||||
| US20050209337 | ||||
| WO2010096123A1 |
Other References:
平山令明,有機化合物結晶作製ハンドブック,2008年,p.17-23,37-40,45-51,57-65
Attorney, Agent or Firm:
Junji Yuda
Noriyuki Takebayashi
Noriyuki Takebayashi