Title:
脂肪肝疾患の予防又は治療用組成物
Document Type and Number:
Japanese Patent JP6490097
Kind Code:
B2
Abstract:
The present invention relates to a pharmaceutical composition for preventing or treating fatty liver diseases, containing (tetrahydropyran-4-yl)-[2-phenyl-5-(1,1-dioxo-thiomorpholin-4-yl)methyl-1H-indol-7-yl]amine or a pharmaceutically acceptable salt thereof as active ingredients. (Tetrahydropyran-4-yl)-[2-phenyl-5-(1,1-dioxo-thiomorpholin-4-yl)methyl-1H-indol-7-yl]amine or a pharmaceutically acceptable salt thereof, according to the present invention, can effectively inhibit fatty liver, hepatitis and hepatic fibrosis and can be useful for preventing or treating NAFLD, and in particular, NASH.
Inventors:
Kim Seung Ha
Kim Hyun Jin
Park Hisul
Anne Seohyun
Song Min Ho
Jung Hyo Kyung
Kim Hyun Jin
Park Hisul
Anne Seohyun
Song Min Ho
Jung Hyo Kyung
Application Number:
JP2016563061A
Publication Date:
March 27, 2019
Filing Date:
April 17, 2015
Export Citation:
Assignee:
LG HAUSYS,LTD.
International Classes:
A61K31/541; A61P1/16; A61P3/06
Domestic Patent References:
| JP2010536846A | ||||
| JP2011509255A |
Other References:
大石俊之、寺井崇二、坂井田功,NASH/NAFLDと酸化ストレス,臨床栄養,2010年 5月,Vol. 116, No.5,p.694-698
三輪佳行、垣下和美,脂肪肝・非アルコール性脂肪性肝炎,Nutrition Care,2011年,Vol. 4, No. 2,p. 29-35
岡上武,NAFLD,NASHの病因・病態,Pharma Medica,2011年,Vol. 29, No. 10,p. 43-46
三輪佳行、垣下和美,脂肪肝・非アルコール性脂肪性肝炎,Nutrition Care,2011年,Vol. 4, No. 2,p. 29-35
岡上武,NAFLD,NASHの病因・病態,Pharma Medica,2011年,Vol. 29, No. 10,p. 43-46
Attorney, Agent or Firm:
Shinya Mitsuhiro
Takashi Watanabe
Takashi Watanabe