Title:
ウイルス様粒子の精製
Document Type and Number:
Japanese Patent JP6553509
Kind Code:
B2
Abstract:
Methods of purifying virus-like particles (VLPs) that are substantially free of process contaminants and infectious agents. The methods incorporate, for example, low-pH treatment during harvest and/or inactivation by a solvent and/or detergent during VLP capture.
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Inventors:
Taylor, ross
Application Number:
JP2015518633A
Publication Date:
July 31, 2019
Filing Date:
June 24, 2013
Export Citation:
Assignee:
TAKEDA VACCINES,INC.
International Classes:
C12N7/02; C07K1/16; C07K1/18; C07K1/20; C07K1/22
Domestic Patent References:
| JP2010530734A | ||||
| JP2010536832A |
Foreign References:
| WO2011012726A1 | ||||
| WO2012040216A1 | ||||
| US20120156243 | ||||
| US20120141529 | ||||
| US6565905 |
Other References:
LAI H.,Plant Cell Rep,31(Epub 2011 Dec 2),p.573-584
HUHTI L. et al,Arch Virol.,155(2010),p.1855-1858
CHEN Q. ,Biological Engineering,1(4)(2008),p.291-321
KOHO T. et al,Journal of Virological Methods,181(Epub 2012 Jan 14),p.6-11
PEIXOTO C. et al,Journal of Biotechnology,127(2007),p.452-461
AUSAR S. et al.,J. Biol. Chem.,vol.281, no.28,p.19478-19488
YAMAZAKI H. et al.,Biochim. Biophys. Acta,53(1961),p.173-180
ALMANZA H. et al.,Journal of Clinical Microbiology,vol.46, No.12(2008),p.3971-3979
HUHTI L. et al,Arch Virol.,155(2010),p.1855-1858
CHEN Q. ,Biological Engineering,1(4)(2008),p.291-321
KOHO T. et al,Journal of Virological Methods,181(Epub 2012 Jan 14),p.6-11
PEIXOTO C. et al,Journal of Biotechnology,127(2007),p.452-461
AUSAR S. et al.,J. Biol. Chem.,vol.281, no.28,p.19478-19488
YAMAZAKI H. et al.,Biochim. Biophys. Acta,53(1961),p.173-180
ALMANZA H. et al.,Journal of Clinical Microbiology,vol.46, No.12(2008),p.3971-3979
Attorney, Agent or Firm:
Yoshiyuki Inaba
Toshifumi Onuki
Akihiko Eguchi
Kazuhiko Naito
Toshifumi Onuki
Akihiko Eguchi
Kazuhiko Naito