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Title:
ポリアミノ酸の製造方法
Document Type and Number:
Japanese Patent JP6587937
Kind Code:
B2
Abstract:
The present invention relates to a graft copolymer of a poly(amino acid) or a salt thereof and a hydrophobic primary amine compound or a salt thereof ( e.g., a graft copolymer (³-PGA-PAE) of poly(³-glutamic acid) (³-PGA) and phenylalanine ethyl ester (PAE)), an ionized graft copolymer of a poly(amino acid) or a salt thereof and a hydrophobic primary amine compound or a salt thereof, nanoparticles containing the ionized graft copolymer, and a production method thereof. The nanoparticles acquired in this way are useful as an adjuvant for producing a vaccine.

Inventors:
Mitsuhisa Yamano
Toshiaki Nagata
Hideki Saito
Application Number:
JP2015524087A
Publication Date:
October 09, 2019
Filing Date:
June 25, 2014
Export Citation:
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Assignee:
Takeda GmbH
International Classes:
C08G69/10; A61K39/39; C08J3/14
Domestic Patent References:
JP2006510792A
JP2002519457A
Attorney, Agent or Firm:
Takuji Yamada
Tsuyoshi Sato