Title:
ドーパデカルボキシラーゼ阻害剤組成物
Document Type and Number:
Japanese Patent JP6591995
Kind Code:
B2
Abstract:
The present invention provides highly stable carbidopa-based pharmaceutical compositions comprising an antioxidant combination consisting of ascorbic acid and at least one additional antioxidant, wherein said combination strongly inhibits carbidopa degradation. These compositions may further comprise levodopa and/or one or both of arginine and meglumine, and are beneficial in treatment of a disease, disorder or condition associated with loss of dopamine or dopaminergic neurons, e.g., Parkinson's disease.
Inventors:
Jacobi-Shrimp, Olong
Application Number:
JP2016556969A
Publication Date:
October 16, 2019
Filing Date:
March 12, 2015
Export Citation:
Assignee:
NEURODERM LTD
International Classes:
A61K31/198; A61K9/06; A61K9/08; A61K9/10; A61K9/107; A61K9/14; A61K9/19; A61K47/02; A61K47/18; A61K47/20; A61K47/22; A61K47/34; A61K47/42; A61P25/16
Domestic Patent References:
| JP2013545745A |
Attorney, Agent or Firm:
Harakenzo world patent & trademark