Title:
脱細胞化生体組織マトリクス材料に基づいた骨修復のための複合材料およびそれを調製する方法
Document Type and Number:
Japanese Patent JP6621539
Kind Code:
B2
Abstract:
A composite material for bone repair based on a decellularized biological tissue matrix material and a preparation method thereof. The composite material for bone repair comprises an organic phase of a microfibrillar decellularized animal tissue matrix material and an inorganic phase of a calcium salt bioceramic or other inorganic bioglass. A preparation process for the composite material for bone repair does not need physical or chemical crosslinking. The composite material for bone repair has a three-dimensional porous network structure, and protein components in the biological tissue matrix material maintain a natural triplex structure. The composite material for bone repair has excellent biocompatibility, biodegradability, osteoconductivity, osteoinductivity, and osteogenecity, also has certain mechanical strength and shape memory function, and can be used as a bone filling material or a repair material for large-area bone defect.
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Inventors:
Liao Hua
You Chunhua
The An Tao
You Shaohua
You Chunhua
The An Tao
You Shaohua
Application Number:
JP2018536329A
Publication Date:
December 18, 2019
Filing Date:
November 21, 2016
Export Citation:
Assignee:
Hancho Huamai Medical Devices Company Limited
International Classes:
A61L27/36; A61L27/04; A61L27/10; A61L27/12; A61L27/38; A61L27/40; A61L27/58
Foreign References:
| CN101417145A | ||||
| US20140255489 | ||||
| US20150343117 | ||||
| US20150065947 | ||||
| CN103341206A | ||||
| CN103055352A | ||||
| CN103432627A | ||||
| CN101417151A |
Other References:
結合組織の定義と分類,2008年,p.1-32,URL,www.kms.ac.jp/~anatomy2/Histology6.pdf
あたらしい皮膚科学,2011年 3月,第2版,p.13-16
Chemical Engineering Journal,2008年,Vol.137,p.102-121
Biomaterials,2011年,Vol.32,p.3233-3243
J. Biomed. Mater. Res. Part A,2011年,Vol.99A,p.283-294
Trends in Biotechnology,2013年,Vol.31,p.169-176
あたらしい皮膚科学,2011年 3月,第2版,p.13-16
Chemical Engineering Journal,2008年,Vol.137,p.102-121
Biomaterials,2011年,Vol.32,p.3233-3243
J. Biomed. Mater. Res. Part A,2011年,Vol.99A,p.283-294
Trends in Biotechnology,2013年,Vol.31,p.169-176
Attorney, Agent or Firm:
Hayashi Ichiyoshi
Tetsuo Shiba
Takuya Saito
Iwaike Mitsuru
Kazuhiro Kosuga
Hiroshi Hayashi
Tetsuo Shiba
Takuya Saito
Iwaike Mitsuru
Kazuhiro Kosuga
Hiroshi Hayashi