ヘテロ型単分散ポリエチレングリコール、ヘテロ型単分散ポリエチレングリコール製造用中間体の製造方法

Title:

ヘテロ型単分散ポリエチレングリコール、ヘテロ型単分散ポリエチレングリコール製造用中間体の製造方法

Document Type and Number:

Japanese Patent JP6638970

Kind Code:

B2

Abstract:

Provided is a hetero type monodispersed polyethylene glycol which contains a compound represented by formula (1) ((1): NH 2 -(CH 2 CH 2 O) a -CH 2 CH 2 COOH (in formula (1), a is an integer between 6 and 40)) and in which the following each satisfy a specified relational expression: (A) a chromatogram detected by a differential refractometer when separation is carried out using reversed phase chromatography; (B) a chromatogram detected by a differential refractometer when separation is carried out using cation exchange chromatography; and (C) a chromatogram detected by a differential refractometer when the hetero type monodispersed polyethylene glycol containing a compound represented by formula (1) is derivatized and separation is carried out using anion exchange chromatography.

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Inventors:

Kanahara number
Takahiro Muraoka
Vueblo Adam Marcin
Tomoyuki Otake
Yoshiaki Kang
Uruga Yuki
Ryutaro Imamura

Application Number:

JP2015131744A

Publication Date:

February 05, 2020

Filing Date:

June 30, 2015

Export Citation:

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