Title:
同位体によりコード化されたレポーターによる多重検出
Document Type and Number:
Japanese Patent JP6640785
Kind Code:
B2
Abstract:
Some aspects of this invention provide reagents and methods for the sensitive, quantitative and simultaneous detection of target analytes in complex biological samples by liquid chromatography tandem mass spectrometry (LC MS/MS). Some aspects of this invention provide affinity reagents encoded with mass reports for the sensitive and quantitative translation of an analyte of interest into a mass tag. The regents and methods provided herein have general utility in analyte detection and encoding, for example, in biomolecular profiling, molecular diagnostics, and biochemical encoding.
Inventors:
Kwon, Gabriel, A.
Buhatia, Sanguita, N.
Buhatia, Sanguita, N.
Application Number:
JP2017100986A
Publication Date:
February 05, 2020
Filing Date:
May 22, 2017
Export Citation:
Assignee:
MASSACHUSETTS INSTITUTE OF TECHNOLOGY
International Classes:
G01N27/62; G01N33/68
Domestic Patent References:
| JP2004506900A | ||||
| JP2009524688A | ||||
| JP2007024631A | ||||
| JP2009538430A |
Foreign References:
| WO2008072676A1 | ||||
| US20100240050 | ||||
| US20080026480 |
Attorney, Agent or Firm:
Kiyoji Kuzuwa