Title:
ピラゾール誘導体の製造方法
Document Type and Number:
Japanese Patent JP6658736
Kind Code:
B2
Abstract:
The invention relates to a method of producing a pyrazole derivative represented by the following formula (6), which comprises reacting a compound represented by the following formula (5) with an oxidant;whereinRis a hydrogen atom or a halogen atom,Ris a Calkyl group,Ris a hydrogen atom or a Calkyl group,Xand Xare each independently a fluorine atom or a chlorine atom, andZis a hydrogen atom or a Calkyl group.
Inventors:
Yuichiro Ishibashi
Ohsuke Yosuke
Miyake Tokuaki
Yusuke Yamazaki
Shota Shimizu
Ohsuke Yosuke
Miyake Tokuaki
Yusuke Yamazaki
Shota Shimizu
Application Number:
JP2017508374A
Publication Date:
March 04, 2020
Filing Date:
March 23, 2016
Export Citation:
Assignee:
AGC Inc.
International Classes:
C07D231/14; C07D231/12
Domestic Patent References:
| JP2010531314A | ||||
| JP2010534626A | ||||
| JP2010501502A | ||||
| JP2007509850A |
Foreign References:
| WO2014160668A1 | ||||
| WO2012176717A1 | ||||
| WO2012009009A2 |
Other References:
Aline TOUZOT et al,Synthesis of trifluoromethylated pyrazoles from trifluoromethylenaminones and monosubstituted hydrazines,Journal of Fluorine Chemistry,2004年,vol.125,p.1299-1304,ISSN:0022-1139
Shiv. P. SINGH et al,A Facile Synthesis of 5-Methyl-1-(phenyl/heterocyclyl)-4-trifluoroacethylpyrazoles,Journal of Chemical Research Synopses,1997年,no.4,p.142-143,ISSN:0308-2342
GHOSH C. K. et al,Heterocyclic System II. Electrophilic Substitution on 1-Phenyl-4-(2-hydroxybenzoyl)pyrazole,Journal of the Indian Chemical Society,1978年,vol.55, no.3,p.268-271,ISSN:0019-4522
ZIKAN V et al,Substanzen mit Antineoplastischer Wirkung XIX. Substituterte Pyrazole Durch Reaktion Von beta-4-Methoxybenzoyl-beta-Chlor(brom)acrylsaure mit Diazomethan,Collection of Czechoslovak Chemical Communications,1967年,vol.32, no.10,p.3587-3596,ISSN:1212-6950
OKADA Etsuji et al,Facile Synthetic Methods for 3- and 5-Trifluoromethyl-4-Trifluoroacetyl-Pyrazoles and Their Conversion into Pyrazole-4-Carboxylic Acids,Heterocycles,1992年,vol.34, no.4,p.791-798,ISSN:1881-0942
Tanaka Kiyoshi et al,Reactions of Trifluoroacetonitrile Oxide or -nitrilimines with beta-Diketones and beta-Keto Esters,Bulletin of Chemical Society of Japan,1986年,vol.59,p.2631-2632,ISSN:0009-2673
Shiv. P. SINGH et al,A Facile Synthesis of 5-Methyl-1-(phenyl/heterocyclyl)-4-trifluoroacethylpyrazoles,Journal of Chemical Research Synopses,1997年,no.4,p.142-143,ISSN:0308-2342
GHOSH C. K. et al,Heterocyclic System II. Electrophilic Substitution on 1-Phenyl-4-(2-hydroxybenzoyl)pyrazole,Journal of the Indian Chemical Society,1978年,vol.55, no.3,p.268-271,ISSN:0019-4522
ZIKAN V et al,Substanzen mit Antineoplastischer Wirkung XIX. Substituterte Pyrazole Durch Reaktion Von beta-4-Methoxybenzoyl-beta-Chlor(brom)acrylsaure mit Diazomethan,Collection of Czechoslovak Chemical Communications,1967年,vol.32, no.10,p.3587-3596,ISSN:1212-6950
OKADA Etsuji et al,Facile Synthetic Methods for 3- and 5-Trifluoromethyl-4-Trifluoroacetyl-Pyrazoles and Their Conversion into Pyrazole-4-Carboxylic Acids,Heterocycles,1992年,vol.34, no.4,p.791-798,ISSN:1881-0942
Tanaka Kiyoshi et al,Reactions of Trifluoroacetonitrile Oxide or -nitrilimines with beta-Diketones and beta-Keto Esters,Bulletin of Chemical Society of Japan,1986年,vol.59,p.2631-2632,ISSN:0009-2673
Attorney, Agent or Firm:
Takashima Ichi
Kyoko Doi
Mitsunori Kamata
Yaeko Tamura
Junzo Koike
Hirofumi Toma
Atsuko Akai
Tomiya Tozaki
Kyoko Doi
Mitsunori Kamata
Yaeko Tamura
Junzo Koike
Hirofumi Toma
Atsuko Akai
Tomiya Tozaki