Title:
甲状腺刺激ホルモンレセプター抗体アイソタイプ測定を用いたバセドウ病の病態診断キット及びバセドウ病の病態の診断方法
Document Type and Number:
Japanese Patent JP6667806
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To provide a kit and method for testing whether a Basedow disease is hyperthyroidism or hypothyroidism.SOLUTION: The present invention provides a diagnosis kit for diagnosing Basedow disease, including a labeled anti-IgM antibody that binds to a thyroid-stimulating hormone receptor antibody, and a labeled anti-IgG antibody that binds to the thyroid-stimulating hormone receptor antibody. A ratio of an amount of the anti-IgM antibody bound to the thyroid-stimulating hormone receptor antibody to an amount of the anti-IgG antibody bound thereto is shown as a clinical indicator of Basedow disease.SELECTED DRAWING: Figure 2
Inventors:
Yoshiko Nagata
Kazuhiko Hayashi
Keisuke Kumada
Kazuhiko Hayashi
Keisuke Kumada
Application Number:
JP2016087002A
Publication Date:
March 18, 2020
Filing Date:
April 25, 2016
Export Citation:
Assignee:
National University Corporation Tottori University
International Classes:
G01N33/53; G01N33/543
Domestic Patent References:
| JP2002048793A | ||||
| JP2013238502A |
Foreign References:
| CN104628843A |
Other References:
NAGATA et al.,Production of thyrotropin receptor antibodies in acute phase of infectious mononucleosis due to Epstein-Barr virus primary infection: a case report of a child.,Springer plus,2015年 8月27日,4:456,PP.1-5
Attorney, Agent or Firm:
sk patent corporation
Akihiko Okuno
Hiroyuki Ito
Akihiko Okuno
Hiroyuki Ito