Title:
ＦＸＲ／ＴＧＲ５アゴニストとしての胆汁酸誘導体およびその使用方法
Document Type and Number:
Japanese Patent JP6785788
Kind Code:
B2
Abstract:
The present invention provides compounds represented by Formula I, or pharmaceutically acceptable salts, stereoisomers, solvates, hydrates or combination thereof,The invention also provides pharmaceutical compositions comprising these compounds and methods of using this compounds for treating FXR-mediated or TGR5-mediated diseases or conditions.
Inventors:
Wang, Guotian
Ol, Yat, Sun
Shen, Rui Chao
Shin, Xue Chao
Ron, Gian
Die pen
Bullet, Granger
F, Jin
Ol, Yat, Sun
Shen, Rui Chao
Shin, Xue Chao
Ron, Gian
Die pen
Bullet, Granger
F, Jin
Application Number:
JP2017550939A
Publication Date:
November 18, 2020
Filing Date:
March 30, 2016
Export Citation:
Assignee:
Enanta Pharmaceuticals, Inc.
International Classes:
C07J41/00; A61K31/575; A61K31/58; A61P1/00; A61P1/16; A61P3/00; A61P3/06; A61P3/10; A61P5/50; A61P9/00; A61P9/10; A61P9/12; A61P13/12; A61P31/12; A61P35/00; A61P37/02; A61P37/06; A61P43/00; C07J43/00
Domestic Patent References:
| JP11109628A |
Foreign References:
| WO2002028881A1 | ||||
| KR1020090104622A |
Other References:
Collection Czechoslovak Chem. Commun.,1986年,51,1722-1730
J. Med. Chem.,2004年,47,4559-4569
J. Med. Chem.,2006年,49,4208-4215
Bioorg. Med. Chem.,2011年,19,2650-2658
J. Med. Chem.,2004年,47,4559-4569
J. Med. Chem.,2006年,49,4208-4215
Bioorg. Med. Chem.,2011年,19,2650-2658
Attorney, Agent or Firm:
Ryoichi Takaoka
Nao Oda
Akiyo Iwahori
Kaoru Takahashi
Nao Oda
Akiyo Iwahori
Kaoru Takahashi