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Title:
チェックポイントキナーゼ１（ＣＨＫ１）阻害剤として有用な３，５−二置換ピラゾール、並びにその調製及び用途
Document Type and Number:
Japanese Patent JP6794609
Kind Code:
B2
Abstract:
The present invention provides compounds of formula (I) which are potent inhibitors of Chk1 and have the structural formula below:wherein R1, R2, R3, R4, and R5 are as defined herein. Pharmaceutical compositions comprising the compounds, uses thereof and their preparation process are also provided.

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Inventors:
Chai shan
Kian, Changen
Wang, Janong Daniel
Application Number:
JP2018541333A
Publication Date:
December 02, 2020
Filing Date:
February 04, 2016
Export Citation:
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Assignee:
PHARMAENGINE, INC.
International Classes:
C07D403/12; A61K31/4745; A61K31/497; A61K45/00; A61P35/00; A61P35/02; A61P43/00
Domestic Patent References:
JP2012512249A
JP2006528661A
Foreign References:
WO2015120390A1
US20110144126
Other References:
Molecular Cancer Therapeutics,2015年,14(9),p.2004-2013
Attorney, Agent or Firm:
Ikeda adult
Junichiro Sakamaki
Masakazu Noda



 
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