Title:
うつ病の治療方法
Document Type and Number:
Japanese Patent JP6801129
Kind Code:
B2
Abstract:
The present disclosure relates to methods of transitioning patients or obese patients being treated with vortioxetine to treatment with a monoamine oxidase inhibitor (MAOI). The methods provided include delaying administration of the MAOI for certain time periods after stopping administration of vortioxetine. The patients or obese patients possess various capabilities of metabolizing vortioxetine. The current disclosure also includes methods of switching patients to a MAOI intended to treat psychiatric disorders while being treated with vortioxetine. The methods disclosed further comprise determining vortioxetine plasma clearance and washout time for patients with different body fat status and/or different CYP2D6 metabolizer status.
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Inventors:
Shrinivasan, Thunder
Butterfly, christina
Butterfly, christina
Application Number:
JP2019566940A
Publication Date:
December 16, 2020
Filing Date:
March 30, 2017
Export Citation:
Assignee:
Rundle Research, LRC
International Classes:
A61K31/495; A61P25/22; A61P25/24; A61P43/00
Foreign References:
| WO2015134585A1 |
Other References:
Highlights of Prescribing Information, BRINTELLIX,2013年 9月,pp.1-29.
CHINEY, M. et al.,The FASEB Journal,2010年 4月 1日,Vol.24, No.1_supplement,URL,https://www.fasebj.org/doi/abs/10.1096/fasebj.24.1_supplement.967.11
CHINEY, M. et al.,The FASEB Journal,2010年 4月 1日,Vol.24, No.1_supplement,URL,https://www.fasebj.org/doi/abs/10.1096/fasebj.24.1_supplement.967.11
Attorney, Agent or Firm:
Yoshiyuki Inaba
Toshifumi Onuki
Akihiko Eguchi
Kazuhiko Naito
Toshifumi Onuki
Akihiko Eguchi
Kazuhiko Naito