Title:
アシルアミノ酸の生成
Document Type and Number:
Japanese Patent JP6803434
Kind Code:
B2
Abstract:
In certain embodiments, the present invention comprises compositions and methods useful in the generation of acyl amino acids. In certain embodiments, the present invention provides an engineered polypeptide comprising a peptide synthetase domain; in some such embodiments, the engineered polypeptide comprises only a single peptide synthetase domain. In some embodiments, the present invention provides an engineered peptide synthetase that is substantially free of a thioesterase domain, and/or a reductase domain. In certain embodiments, the present invention provides an acyl amino acid composition comprising a plurality of different forms of an acyl amino acid. In some such compositions, substantially all of the acyl amino acids within the composition contain the same amino acid moiety and differ with respect to acyl moiety. We also described populations where the fatty acid is for example 95% one length (C14, myristic).
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Inventors:
Kevin A. Jarrell
Gabriel A. Reznik
Prashenz Bishwanatsu
Michelle pin
Gabriel A. Reznik
Prashenz Bishwanatsu
Michelle pin
Application Number:
JP2019154479A
Publication Date:
December 23, 2020
Filing Date:
August 27, 2019
Export Citation:
Assignee:
Modular Genetics, Incorporated
International Classes:
C12P13/04; C12N1/21; C12N9/00; C12P13/16
Domestic Patent References:
| JP2005508622A |
Foreign References:
| WO2008131002A2 | ||||
| WO2008131014A1 |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto