Title:
オキサスピロ誘導体、その製造方法、及び医薬におけるその適用
Document Type and Number:
Japanese Patent JP6824502
Kind Code:
B2
Abstract:
The present invention relates to an oxa spiro derivative, a preparation method therefor, and applications thereof in medicines. Particularly, the present invention relates to an oxa spiro derivative represented by formula (I), a preparation method therefor, and a pharmaceutical composition comprising the derivative, applications thereof as an MOR receptor agonist, and applications in the preparation of drugs for treating and/or preventing pains and pains-related diseases. Substituent groups in the formula (I) are same as definitions in the specification.
Inventors:
Lee, Shin
Phone, Vincian
Chen, Yang
Ryu, Tao
Hua, Fong
Hua, Min Shun
Tao, Weikan
Sun, Piao Yang
Phone, Vincian
Chen, Yang
Ryu, Tao
Hua, Fong
Hua, Min Shun
Tao, Weikan
Sun, Piao Yang
Application Number:
JP2018515975A
Publication Date:
February 03, 2021
Filing Date:
September 30, 2016
Export Citation:
Assignee:
JIANGSU HENGRUI MEDICINE CO.,LTD.
SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD.
SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD.
International Classes:
C07D405/04; A61K31/4433; A61K31/4436; A61K31/4709; A61P1/04; A61P7/04; A61P9/00; A61P11/00; A61P13/02; A61P15/00; A61P25/00; A61P25/04; A61P25/18; A61P29/00; A61P35/00; A61P35/02; A61P37/04; A61P43/00; C07D405/14; C07D409/14
Domestic Patent References:
| JP2010516810A |
Foreign References:
| WO2012129495A1 |
Attorney, Agent or Firm:
Xie Takamine
Tadayuki Motoyama
Kenji Tobetsu
Tadayuki Motoyama
Kenji Tobetsu