Title:
複素環化合物
Document Type and Number:
Japanese Patent JP6832342
Kind Code:
B2
Abstract:
The present invention provides a compound having an MAGL inhibitory action, and useful as an agent for the prophylaxis or treatment of neurodegenerative diseases (e.g., Alzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, traumatic brain injury, glaucoma, multiple sclerosis etc.), anxiety disorder, pains (e.g., inflammatory pain, cancerous pain, neurogenic pain etc.), epilepsy, depression and the like. The present invention relates to a compound represented by the formula (I):
wherein each symbol is as defined in the specification, or a salt thereof.
Inventors:
Shuhei Ikeda
Hideyuki Sugiyama
Meeting Junpei Ta
Hidekazu Tokuhara
Tomohiro Okawa
Yuya Oguro
Minoru Nakamura
Murakami Masataka
Hideyuki Sugiyama
Meeting Junpei Ta
Hidekazu Tokuhara
Tomohiro Okawa
Yuya Oguro
Minoru Nakamura
Murakami Masataka
Application Number:
JP2018509415A
Publication Date:
February 24, 2021
Filing Date:
March 30, 2017
Export Citation:
Assignee:
Takeda GmbH
International Classes:
C07D487/10; A61K31/407; A61K31/4184; A61K31/422; A61K31/423; A61K31/424; A61K31/427; A61K31/428; A61K31/4439; A61K31/454; A61K31/4545; A61K31/496; A61K31/506; A61K31/537; A61K31/5386; A61P21/02; A61P25/00; A61P25/04; A61P25/08; A61P25/14; A61P25/16; A61P25/22; A61P25/24; A61P25/28; A61P43/00; C07D498/10
Domestic Patent References:
| JP2013542265A | ||||
| JP2013537920A | ||||
| JP2012524801A | ||||
| JP2008024693A | ||||
| JP2005510476A | ||||
| JP2015513552A | ||||
| JP2015500214A | ||||
| JP6653319B2 |
Foreign References:
| WO2015046193A1 | ||||
| WO2015068856A1 | ||||
| WO2015032286A1 | ||||
| WO2015103508A1 | ||||
| WO2015103509A1 |
Attorney, Agent or Firm:
Takashima Ichi
Kyoko Doi
Mitsunori Kamata
Yaeko Tamura
Hirofumi Toma
Atsuko Akai
Tomiya Tozaki
Kyoko Doi
Mitsunori Kamata
Yaeko Tamura
Hirofumi Toma
Atsuko Akai
Tomiya Tozaki