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Title:
液性免疫誘導促進用組成物及びワクチン医薬組成物
Document Type and Number:
Japanese Patent JP6893075
Kind Code:
B2
Abstract:
The present invention aims to provide a composition for promoting humoral immunity induction and a vaccine pharmaceutical composition that can be universally used for various antigens in inducing humoral immunity to antigens, contain a Th2 reaction promoter, and exerts a high humoral immunity inducing effect. The present invention relates to a vaccine pharmaceutical composition containing an antigen for humoral immunity induction and at least one Th2 reaction promoter.

Inventors:
Takuya Shishido
Daisuke Asari
Kyohei Matsushita
Mitsuhiko Hori
Application Number:
JP2015154344A
Publication Date:
June 23, 2021
Filing Date:
August 04, 2015
Export Citation:
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Assignee:
NITTO DENKO CORPORATION
International Classes:
A61K39/39; A61K31/137; A61K31/216; A61K31/225; A61K31/404; A61K31/41; A61K31/4184; A61K31/4365; A61K31/445; A61K31/46; A61K31/47; A61K31/485; A61K31/495; A61K31/517; A61K31/5415; A61K31/55; A61K31/5513; A61K31/5517; A61K39/00; A61P37/04
Domestic Patent References:
JP2006508936A
JP2010505769A
JP59205315A
Other References:
埼玉医科大学雑誌,2008年,Vol.35, No.1,pp.33-38
GOREN N. et al,Increases in cyclic AMP levels couple to H1 receptors in atria from autoimmune myocarditis mice.,Cellular Signalling,1995年,vol.7, no.8,p.759-764,特に759頁右欄1-9行
中野和久,CD4+ T細胞の機能的亜群への分化 Th2細胞を誘導する樹状細胞,臨床免疫・アレルギー科,2009年,vol.51, no.5,p.450-455,特に452頁左欄下から4行-同頁右欄4行,452頁右欄下から3行-453頁左欄4行
Е.Р.РУБЦОВА et al,The study of the immunotropic activity of cAMP phosphodiesterase inhibitors caffeine and theophyllin,Farmakologiya Toksikologiya,1986年,vol.49, no.3,p.74-77
KOH W. S. et al,Cyclic AMP is essential factor in immune responses.,Biochemical and Biophysical Research Communications,1995年,vol.206, no.2,p.703-709
田中千賀子ほか,NEW薬理学(改訂第6版),2012年11月20日,第47~49行
Attorney, Agent or Firm:
Atomi International Patent Office