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Title:
クロマトグラムのピーク検出感度の自動決定方法
Document Type and Number:
Japanese Patent JP6926628
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To provide a method for automatically determining peak detection sensitivity with respect to chromatogram of multiple measurement samples different in dilution magnification and concentration.SOLUTION: An analytical curve generation method is the method for measuring samples different in dilution magnification by chromatography. In the method, dilution magnification of a sample for obtaining chromatogram that can detect a specified peak is defined as standard dilution magnification, and peak detection sensitivity in measuring a sample of the standard dilution magnification is defined as standard peak detection sensitivity. Then, when a sample other than the sample of the standard dilution magnification is measured, a value obtained by multiplying the standard peak detection sensitivity by a ratio of the standard dilution magnification to dilution magnification of the sample is used as peak detection sensitivity.SELECTED DRAWING: Figure 5

Inventors:
Haraichi Uematsu
Masashi Horiga
Application Number:
JP2017085291A
Publication Date:
August 25, 2021
Filing Date:
April 24, 2017
Export Citation:
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Assignee:
Tosoh Corporation
International Classes:
G01N30/86
Domestic Patent References:
JP11218530A
JP6148165A
JP2013040879A
JP8035960A
Foreign References:
US20120166101
Other References:
SUGNAUX, F.R. et al.,COMPLETE COMPUTER AUTOMATION OF PREPARATIVE LIQUID CHROMATOGRAPHY THROUGH INTELLIGENT FRACTION COLLECTION, WITH UNLIMITED INJECTION VOLUME AND REPETITIVE COLLECTION OF SEPARATED SOLUTE PEAKS,J. Chromatography,1982年,Vol.248,p.373-389