Title:
ゲノム編集システムおよび使用方法
Document Type and Number:
Japanese Patent JP6937740
Kind Code:
B2
Abstract:
Compositions and methods are provided for genome editing at a target site in the genome of a filamentous fungal cell. The methods and compositions disclosed are drawn to a guide polynucleotide/Cas endonuclease system and donor polynucleotides with shorter homology arms (i.e., less than 500 bps) to a genomic locus of the fungal cell.
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Inventors:
Bao, Kai
Madrid, Susan Manpusty
Schmidt, Brian Ef
Madrid, Susan Manpusty
Schmidt, Brian Ef
Application Number:
JP2018503753A
Publication Date:
September 22, 2021
Filing Date:
July 28, 2016
Export Citation:
Assignee:
Danisco US Inc.
International Classes:
C12N15/09; C12N1/15
Domestic Patent References:
| JP6814142B2 | ||||
| JP6650448B2 | ||||
| JP6814143B2 | ||||
| JP6814141B2 | ||||
| JP2017538425A | ||||
| JP2018504895A | ||||
| JP2017537647A |
Foreign References:
| WO2014093622A2 | ||||
| WO2015054507A1 | ||||
| WO2016110453A1 |
Other References:
LIU R. et al.,Cell Discovery,1 (2015 May 12),15007,doi:10.1038/celldisc.2015.7
DICARLO J. E. et al.,Nucleic Acids Research,vol.41 no.7 (2013),p.4336-4343
PAIX A. et al.,Genetics,vol.198 (2014),p.1347-1356
LIN S. et al.,eLIFE,3 (2014),e04766,doi: 10.7554/eLife.04766
NODVIG C. S. et al.,PLOS ONE,10(7)(2015 Jul 15): e0133085,DOI:10.1371/journal.pone.0133085
DICARLO J. E. et al.,Nucleic Acids Research,vol.41 no.7 (2013),p.4336-4343
PAIX A. et al.,Genetics,vol.198 (2014),p.1347-1356
LIN S. et al.,eLIFE,3 (2014),e04766,doi: 10.7554/eLife.04766
NODVIG C. S. et al.,PLOS ONE,10(7)(2015 Jul 15): e0133085,DOI:10.1371/journal.pone.0133085
Attorney, Agent or Firm:
Yuzo Yamazaki
Toshiaki Akamatsu
Tadao Naito
Chihiro Imai
Toshiaki Akamatsu
Tadao Naito
Chihiro Imai