Title:
骨芽細胞及びその調製方法
Document Type and Number:
Japanese Patent JP6941868
Kind Code:
B2
Abstract:
An object of the present invention is to provide a method for generating an osteoblast that is applicable to repair of a bone defect due to various tumors, injuries, surgeries, etc. and to treatment for bone resorption typified by a periodontal disease, bone fracture, osteoporosis, etc., and that has a low risk of carcinogenesis. Provided as a means for achieving this object is a method for generating an osteoblast from a somatic cell of a mammal, the method comprising introducing Oct9 gene or an expression product thereof into the somatic cell.
Inventors:
Kenta Yamamoto
Tsunataro Kishida
Toshiro Yamamoto
Osamu Matsuda
Tsunataro Kishida
Toshiro Yamamoto
Osamu Matsuda
Application Number:
JP2017536407A
Publication Date:
September 29, 2021
Filing Date:
August 19, 2016
Export Citation:
Assignee:
Kyoto Prefectural University Corporation
International Classes:
C12N15/85; C12N5/077; C12N5/10
Foreign References:
| WO2015012377A1 | ||||
| WO2014129550A1 |
Other References:
PNAS (2015) Vol.112, No.19, pp.6152-6157
Cell Biology International (2010) Vol.34, No.9, pp.877-882
JARO (2008) Vol.9, pp.33-43
Cell Biology International (2010) Vol.34, No.9, pp.877-882
JARO (2008) Vol.9, pp.33-43
Attorney, Agent or Firm:
Takashima Ichi
Mitsunori Kamata
Mitsunori Kamata